Figure 1

The advances and challenges of Gene Therapy for Duchenne Muscular Dystrophy

Jacques P Tremblay* and Jean-Paul Iyombe-Engembe

Published: 25 July, 2017 | Volume 1 - Issue 1 | Pages: 019-036

jgmgt-aid1003-g001

Figure 1:

Diagram of transplantation of allogeneic myoblasts by intramuscular route. a) Injection of allogeneic myoblasts into the patient's muscle with a needle. b) The injected myoblasts migrate to the perimysium space due to the chemotactic gradient. c) The regeneration of part of the patient muscle fiber (blue). d) Muscle regeneration occurs in the necrotic part of the patient's muscle fiber. e) The regenerated part of the muscle fiber express proteins coded by the exogenous nuclei. f) The transplanted myoblasts also form new satellite cells. g) The grafted myoblasts can fuse together. h) This results in the formation of new muscle fibers.

Read Full Article HTML DOI: 10.29328/journal.jgmgt.1001003 Cite this Article Read Full Article PDF

More Images

Similar Articles

Recently Viewed

  • The Bacteriological Profile of Nosocomial Infections at the Army Central Hospital of Brazzaville
    Medard Amona*, Yolande Voumbo Matoumona Mavoungou, Hama Nemet Ondzotto, Benjamin Kokolo, Armel Itoua, Gilius Axel Aloumba and Pascal Ibata Medard Amona*,Yolande Voumbo Matoumona Mavoungou,Hama Nemet Ondzotto,Benjamin Kokolo,Armel Itoua,Gilius Axel Aloumba,Pascal Ibata. The Bacteriological Profile of Nosocomial Infections at the Army Central Hospital of Brazzaville. Int J Clin Microbiol Biochem Technol. 2025: doi: 10.29328/journal.ijcmbt.1001032; 8: 009-022
  • Nasal cytology in patients with previous SARS-CoV-2 infection: occurrence of atypical lymphocytes
    Arturo Armone Caruso*, Anna Miglietta, Giovanni De Rossi, Liliana Nappi, Veronica Viola, Stefano De Rossi, Salvatore Del Prete, Clara Imperatore, Sabato Leo, Daniele Naviglio, Monica Gallo, Daniela Marasco and Lucia Grumetto Arturo Armone Caruso*, Anna Miglietta, Giovanni De Rossi, Liliana Nappi, Veronica Viola, Stefano De Rossi, Salvatore Del Prete, Clara Imperatore, Sabato Leo, Daniele Naviglio, Monica Gallo, Daniela Marasco, Lucia Grumetto. Nasal cytology in patients with previous SARS-CoV-2 infection: occurrence of atypical lymphocytes. Adv Treat ENT Disord. 2023: doi: 10.29328/journal.ated.1001014; 7: 001-006
  • Vestibular-limbic relationships: Brain mapping
    Paolo Gamba* Paolo Gamba*. Vestibular-limbic relationships: Brain mapping. Insights Depress Anxiety. 2018: doi: 10.29328/journal.ida.1001006; 2: 007-013
  • May we feed cancer?
    Maria Grazia Spurio* Maria Grazia Spurio*. May we feed cancer?. Insights Depress Anxiety. 2018: doi: 10.29328/journal.ida.1001005; 2: 001-006
  • Spiritual and religious Islamic perspectives of healing of posttraumatic stress disorder
    Mevludin Hasanović*, Izet Pajević and Osman Sinanović Mevludin Hasanović*,Izet Pajević,Osman Sinanović. Spiritual and religious Islamic perspectives of healing of posttraumatic stress disorder. Insights Depress Anxiety. 2017: doi: 10.29328/journal.hda.1001004; 1: 023-029

Read More

Most Viewed

Read More

Help ?