Review Article
Published: 22 February, 2019 | Volume 2 - Issue 1 | Pages: 001-006
Köbberling-Dunnigan syndrome, also known as partial familial lipodystrophy, is a rare genetic disorder characterized by abnormal distribution of adipose tissues. Many people with Köbberling-Dunnigan syndrome develop insulin resistance, a condition in which body tissues cannot adequately respond to insulin hormone. Insulin is a hormone that helps regulate the level of your blood glucose. Köbberling-Dunnigan syndrome can be due to mutations in several different genes. However, type 2 Köbberling-Dunnigan syndrome is caused by the mutation of the LMNA gene, which is located on the long arm of chromosome 1 as 1q22.
Read Full Article HTML DOI: 10.29328/journal.jgmgt.1001004 Cite this Article Read Full Article PDF
Köbberling-dunnigan syndrome; LMNA; PPARG; PLIN1; AKT2; CIDEC genes; Metabolic disorder
HSPI: We're glad you're here. Please click "create a new Query" if you are a new visitor to our website and need further information from us.
If you are already a member of our network and need to keep track of any developments regarding a question you have already submitted, click "take me to my Query."